One of a kind compact overview of essential topics in internal medicine from Canada’s McMaster university. Originally developed at McMaster University, the birthplace of evidence-based medicine (EBM), and in the Polish Institute for Evidence Based Medicine (PIEBM), and reviewed by renowned experts from South and Southeast Asia to address differences in health-care systems, epidemiology of diseases, availability of diagnostic and therapeutic methods. The latest, state‑of‑the‑art knowledge in the field of broadly understood internal medicine. Applying evidence‑based medicine principles Adapted by nearly 500 South Asian experts to specific local problems and solutions with emphasis on regional aspects of disease prevalence, presentation, diagnosis, and management Perfectly relevant to the target South Asian audience. Expert overview of a wide range of topics, from cardiology and endocrinology to hematology and infectious diseases, reflecting the North American, European, and South Asian approach. Uniformly structured chapters for greater ease of use and quick navigation. Facilitating decision-making through GRADE indicators. For clinicians, including internists, family physicians, hospitalists, medical residents and students, all front-line acute health-care workers, and other medical professionals.