The basic layout of the book remains unchanged presenting the essentials of the subject in a lucid and concise manner. This second edition, like its predecessor, also includes a few new mnemonics, jokes and cartoons to pep up the text. In addition to an update on all the chapters, the most obvious additions in this second edition are the following:

New chapters on pharmacotherapy, pathognomonic signs and symptoms, preventive screening, and adult immunization.

• Cardiology: mitral valve prolapse and cardiomyopathy.
• Endocrinology: pituitary apoplexy, painless thyroiditis, thyroid nodule, and obesity hypoventilation syndrome.
• Gastroenterology: eosiniphilic esophagitis, hepatorenal syndrome, hepatopulmonary syndrome, BuddChiari syndrome, autoimmune hepatitis, and microscopic colitis.
• Hematology: G6PD deficiency, hairy cell leukemia, febrile neutropenia, cancer related anemia, tumor lysis syndrome, and von Willebrand disease.
• Pulmonary: nosocomial pneumonia, reactive airway function syndrome, paradoxical vocal cord motion, pulmonary hypertension, sarcoidosis, and Lofgren’s syndrome.
• Rheumatology: Still’s disease, parvovirus B19 infection, pseudogout, and druginduced lupus.
• Nephrology: calciphylaxis and rhabdomyolysis.
• Neurology: ischemic migraine, paroxysmal hemicrania, transient global amnesia, cerebellar stroke, posterior reversible leukoencephalopathy syndrome, multiple sclerosis, neuroleptic malignant syndrome, normal pressure hydrocephalus, idiopathic intracranial hypertension, sleep apnea syndrome, restless leg syndrome, narcolepsy, REM behavior disorder, and myasthenia gravis.
• Infectious diseases: traveler’s diarrhea, hemolytic uremic syndrome, tick borne diseases, and septic shock.
• Toxicology: salicylate overdose, TCA overdose, toxic alcohols overdose, MDMA overdose, withdrawal syndromes, smoking cessation, and serotonin syndrome

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